Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004321)
Formula	Methylationn
	Reactant	Eriodictyol	Product	Hesperetin
	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Conjugation - Methylationn

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR003839	BE-14348A	Eriodictyol	Oxidation - Hydrolyzationn	BE-14348A	[1]
MR007030	Hesperetin	Eriodictyol	Oxidation - 4'-demethylation	Hesperetin	[2]
MR004320	Naringenin	Eriodictyol	Oxidation - Hydrolyzationn	Naringin	[3]

Other MR(s) Related to The Product of This MR

Other MR(s) That Produce The Product of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR004484	VS-12343	Hesperetin	Oxidation - Deglycosylation	VS-12343	[4]
MR004323	4'-O-Methyl-naringenin	Hesperetin	Oxidation - Hydrolyzationn	Naringin	[3]
MR003857	Isosakuranetin	Hesperetin	Oxidation - Hydrolyzationn	BRN-0183227	[5]
MR004326	Neohesperidin	Hesperetin	Hydrolysis - Hydrolyzation	Naringin	[3]

References
1	Pharmacokinetics and Metabolism of Naringin and Active Metabolite Naringenin in Rats, Dogs, Humans, and the Differences Between Species
2	DrugBank(Pharmacology-Metabolism):Hesperetin
3	Microbial Metabolism of Naringin and the Impact on Antioxidant Capacity
4	Biotransformation of two citrus flavanones by lactic acid bacteria in chemical defined medium
5	Flavanone metabolism in healthy and tumor-bearing rats

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