Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004300)
Formula
SVG example
Reactant Benzoic acid Product Catechol
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010983 Benzoic acid Salicylic acid Unclear - Unclear Benzoic acid [1]
MR000219 Benzoic acid Hippuric acid Conjugation - Glycine Conjugation Amphetamine [2]
MR003836 Benzoic acid 4-Hydroxyhippuric acid Unclear BE-14348A [3]
MR003837 Benzoic acid Hippuric acid Unclear BE-14348A [3]
MR005289 Benzoic acid Benzoyl glucuronide Unclear Cinnamic acid [4]
MR009199 Benzoic acid Hippuric acid Conjugation - Glycination 3,4-Dihydroxycinnamic Acid [5]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012344 HPPH Catechol Unclear - Unclear HPPH [6]
MR010926 Guaiacol Catechol Unclear - Unclear Isovanillin [7]
MR010925 Protocatechuic acid Catechol Unclear - Unclear Isovanillin [7]
MR013587 Pyrogallol Catechol Unclear Epigallocatechin gallate [8]
MR004867 5-methoxysalicylic acid Catechol Multi-steps Reaction - Demethylation; Reduction Naproxen [9]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004868 Catechol Cis-cis muconic acid Unclear Naproxen [9]
References
1 Biosynthesis and metabolism of salicylic acid
2 DrugBank(Pharmacology-Metabolism)Amphetamine
3 High gastrointestinal permeability and local metabolism of naringenin: influence of antibiotic treatment on absorption and metabolism
4 Metabolism of trans-cinnamic acid in the rat and the mouse and its variation with dose
5 In vitro catabolism of 3',4'-dihydroxycinnamic acid by human colonic microbiota
6 Role of CYP2C9, CYP2C19 and EPHX Polymorphism in the Pharmacokinetic of Phenytoin: A Study on Uruguayan Caucasian Subjects
7 The metabolism of vanillin and isovanillin in the rat
8 Absorption, metabolism, bioactivity, and biotransformation of epigallocatechin gallate
9 Utilization of naproxen by Amycolatopsis sp. Poz 14 and detection of the enzymes involved in the degradation metabolic pathway

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