Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010925)
Formula
SVG example
Unclear
Reactant Protocatechuic acid Product Catechol
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012893 4-hydroxylaminobenzoate Protocatechuate Unclear Nitrobenzoate [1]
MR010922 Vanillic acid Protocatechuic acid Unclear - Unclear Isovanillin [2]
MR004360 4-hydroxylaminobenzoate Protocatechuate Unclear Nitrobenzaldehyde [1]
MR004588 DMPE 3,4-Dihydroxybenzoic acid Conjugation - Methylationn Phosethanolamine [3]
MR013910 Mebeverine Metabolite M1 Mebeverine Metabolite M2 Unclear - Unclear Mebeverine [4]
MR013912 Vanillic acid Mebeverine Metabolite M2 Unclear - Unclear Mebeverine [4]
MR004494 3'-4'-Dihydroxyphenylacetic acid 3,4-Dihydroxybenzoic acid Unclear VS-12343 [5]
MR003507 3,4-dihydroxyphenylacetic acid 3,4-Dihydroxybenzoic acid Unclear L-phenylalanine [6]
MR014114 4-Hydroxybenzoic acid 3,4-Dihydroxybenzoic acid Oxidation - Alkyl-chain hydroxylation N-nonylphenol [7]
MR004402 1-(4-hydroxyphenyl)ethanone 3,4-Dihydroxybenzoic acid Oxidation - Hydrolyzationn N-nonylphenol [7]
MR014115 4-Hydroxybenzoic acid 3,4-Dihydroxybenzoic acid Unclear N-nonylphenol [7]
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Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012894 Protocatechuate Alpha-hydroxy-gamma-carboxymuconic semialdehyde Other reaction - Ring cleavage reaction Nitrobenzoate [1]
MR004361 Protocatechuate Nitrobenzaldehyde Metabolite M2 Other reaction - Ring cleavage reaction Nitrobenzaldehyde [1]
MR004495 3,4-Dihydroxybenzoic acid 3-Hydroxybenzoic acid Unclear VS-12343 [5]
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Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012344 HPPH Catechol Unclear - Unclear HPPH [8]
MR004300 Benzoic acid Catechol Unclear Naphthoquinone [9]
MR010926 Guaiacol Catechol Unclear - Unclear Isovanillin [2]
MR013587 Pyrogallol Catechol Unclear Epigallocatechin gallate [10]
MR004867 5-methoxysalicylic acid Catechol Multi-steps Reaction - Demethylation; Reduction Naproxen [11]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004868 Catechol Cis-cis muconic acid Unclear Naproxen [11]
References
1 Biodegradation of 4-nitrotoluene by Pseudomonas sp. strain 4NT
2 The metabolism of vanillin and isovanillin in the rat
3 Phospholipid N-Methyltransferases Produce Various Methylated Phosphatidylethanolamine Derivatives in Thermophilic Bacteria
4 Investigative implications of the instability and metabolism of mebeverine
5 Biotransformation of two citrus flavanones by lactic acid bacteria in chemical defined medium
6 Catabolism of L-phenylalanine and L-tyrosine by Rhodobacter sphaeroides OU5 occurs through 3,4-dihydroxyphenylalanine Res Microbiol. 2007 Jul-Aug;158(6):506-11. doi: 10.1016/j.resmic.2007.04.008.
7 4-n-nonylphenol degradation by the genus Metarhizium with cytochrome P450 involvement
8 Role of CYP2C9, CYP2C19 and EPHX Polymorphism in the Pharmacokinetic of Phenytoin: A Study on Uruguayan Caucasian Subjects
9 Identification of naphthalene metabolism by white rot fungus Pleurotus eryngii
10 Absorption, metabolism, bioactivity, and biotransformation of epigallocatechin gallate
11 Utilization of naproxen by Amycolatopsis sp. Poz 14 and detection of the enzymes involved in the degradation metabolic pathway

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