Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004687)
Formula
SVG example
20-reduction
Reactant Methylprednisolone M1 Metabolite Product Methylprednisolone M12 Metabolite
Reactant Info Product Info
Metabolic Enzyme 20-ketosteroid reductase (20-hydroxysteroid dehydrogenase) (kduD) DME Info
Metabolic Type Reduction - 20-reduction
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004685 Methylprednisolone Methylprednisolone M1 Metabolite Oxidation - 11-oxidation Methylprednisolone [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004686 Methylprednisolone M1 Metabolite Methylprednisolone M11 Metabolite Reduction - 20-reduction Methylprednisolone [1], [2]
MR004688 Methylprednisolone M1 Metabolite Methylprednisolone M8 Metabolite Oxidation - 16-hydroxylation Methylprednisolone [1]
References
1 Urinary profile of methylprednisolone and its metabolites after oral and topical administrations
2 Carbonyl reduction pathways in drug metabolism

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