Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004811)
Formula
CES1 ...
SVG example
Reactant Mycophenolate mofetil Product Mycophenolic acid
Reactant Info Product Info
Metabolic Enzyme Carboxylesterase 1 (CES1) DME Info
Carboxylic ester hydrolase (CEH) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004820 Mycophenolate mofetil 7-O-glucoside Unclear Mycophenolate mofetil [1]
MR004821 Mycophenolate mofetil Acyl glucuronide Unclear Mycophenolate mofetil [1]
MR004815 Mycophenolate mofetil Mycophenolic acid glucuronide Conjugation - Glucuronidation Mycophenolate mofetil [2]
MR004816 Mycophenolate mofetil Mycophenolic acyl-glucuronide (AcMPAG) Conjugation - Glucuronidation Mycophenolate mofetil [2]
MR004817 Mycophenolate mofetil N-(2-carboxymethyl)-morpholine Hydrolysis - Hydrolyzation Mycophenolate mofetil [2]
MR004818 Mycophenolate mofetil N-(2-hydroxyethyl)-morpholine Unclear Mycophenolate mofetil [2]
MR004819 Mycophenolate mofetil N-(2-hydroxyethyl)-morpholine N-oxide Unclear Mycophenolate mofetil [2]
References
1 Mycophenolate mofetil in organ transplantation: focus on metabolism, safety and tolerability
2 PharmGKB summary: mycophenolic acid pathway. Pharmacogenet Genomics. 2014 Jan;24(1):73-9.

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