Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004862)
Formula
SVG example
Reactant Naproxen metabolite M1 Product Naproxen metabolite M2
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008771 Didanosine Hypoxanthine Unclear - Unclear Didanosine [1]
MR005024 Fluoxymesterone Fluoxymesterone Metabolite A7 Reduction - Reduction Fluoxymesterone [2]
MR007507 Inosine Hypoxanthine Unclear Inosine [3], [4]
MR004861 Naproxen Naproxen metabolite M1 Oxidation - Hydrolyzationn Naproxen [5]
MR000078 Inosine Hypoxanthine Other reaction - Phosphorylation Adenosine [6], [7]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005025 Fluoxymesterone Metabolite A7 Fluoxymesterone Metabolite A2 Oxidation - Hydrolyzationn Fluoxymesterone [2]
MR005026 Fluoxymesterone Metabolite A7 Fluoxymesterone Metabolite A8 Unclear Fluoxymesterone [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004863 Naproxen metabolite M2 Naproxen metabolite M3 Unclear Naproxen [5]
References
1 Comparative metabolism of the antiviral dimer 3'-azido-3'-deoxythymidine-P-2',3'-dideoxyinosine and the monomers zidovudine and didanosine by rat, monkey, and human hepatocytes
2 Elucidation of urinary metabolites of fluoxymesterone by liquid chromatography-tandem mass spectrometry and gas chromatography-mass spectrometry
3 Metabolism of nicotinamide, adenine and inosine in developing microspore-derived canola (Brassica napus) embryos
4 Inosine in Biology and Disease
5 Utilization of naproxen by Amycolatopsis sp. Poz 14 and detection of the enzymes involved in the degradation metabolic pathway
6 Adenosine Metabolism: Emerging Concepts for Cancer Therapy Cancer Cell. 2019 Dec 9;36(6):582-596. doi: 10.1016/j.ccell.2019.10.007.
7 Purine signaling pathway dysfunction in autism spectrum disorders: Evidence from multiple omics data. Front Mol Neurosci. 2023 Feb 3;16:1089871. doi: 10.3389/fnmol.2023.1089871.

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