Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005024)
Formula
SVG example
Reduction
Reactant Fluoxymesterone Product Fluoxymesterone Metabolite A7
Reactant Info Product Info
Metabolic Type Reduction - Reduction
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005020 Fluoxymesterone Fluoxymesterone Metabolite A3 Unclear Fluoxymesterone [1]
MR005027 Fluoxymesterone Fluoxymesterone Metabolite A4 Oxidation - Hydrolyzationn Fluoxymesterone [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008771 Didanosine Hypoxanthine Unclear - Unclear Didanosine [2]
MR007507 Inosine Hypoxanthine Unclear Inosine [3], [4]
MR004861 Naproxen Naproxen metabolite M1 Oxidation - Hydrolyzationn Naproxen [5]
MR000078 Inosine Hypoxanthine Other reaction - Phosphorylation Adenosine [6], [7]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005025 Fluoxymesterone Metabolite A7 Fluoxymesterone Metabolite A2 Oxidation - Hydrolyzationn Fluoxymesterone [1]
MR005026 Fluoxymesterone Metabolite A7 Fluoxymesterone Metabolite A8 Unclear Fluoxymesterone [1]
MR004862 Naproxen metabolite M1 Naproxen metabolite M2 Unclear Naproxen [5]
References
1 Elucidation of urinary metabolites of fluoxymesterone by liquid chromatography-tandem mass spectrometry and gas chromatography-mass spectrometry
2 Comparative metabolism of the antiviral dimer 3'-azido-3'-deoxythymidine-P-2',3'-dideoxyinosine and the monomers zidovudine and didanosine by rat, monkey, and human hepatocytes
3 Metabolism of nicotinamide, adenine and inosine in developing microspore-derived canola (Brassica napus) embryos
4 Inosine in Biology and Disease
5 Utilization of naproxen by Amycolatopsis sp. Poz 14 and detection of the enzymes involved in the degradation metabolic pathway
6 Adenosine Metabolism: Emerging Concepts for Cancer Therapy Cancer Cell. 2019 Dec 9;36(6):582-596. doi: 10.1016/j.ccell.2019.10.007.
7 Purine signaling pathway dysfunction in autism spectrum disorders: Evidence from multiple omics data. Front Mol Neurosci. 2023 Feb 3;16:1089871. doi: 10.3389/fnmol.2023.1089871.

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