Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005025)
Formula
SVG example
Hydrolyzationn
Reactant Fluoxymesterone Metabolite A7 Product Fluoxymesterone Metabolite A2
Reactant Info Product Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008771 Didanosine Hypoxanthine Unclear - Unclear Didanosine [1]
MR005024 Fluoxymesterone Fluoxymesterone Metabolite A7 Reduction - Reduction Fluoxymesterone [2]
MR007507 Inosine Hypoxanthine Unclear Inosine [3], [4]
MR004861 Naproxen Naproxen metabolite M1 Oxidation - Hydrolyzationn Naproxen [5]
MR000078 Inosine Hypoxanthine Other reaction - Phosphorylation Adenosine [6], [7]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005026 Fluoxymesterone Metabolite A7 Fluoxymesterone Metabolite A8 Unclear Fluoxymesterone [2]
MR004862 Naproxen metabolite M1 Naproxen metabolite M2 Unclear Naproxen [5]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005028 Fluoxymesterone Metabolite A4 Fluoxymesterone Metabolite A2 Reduction - Reduction Fluoxymesterone [2]
References
1 Comparative metabolism of the antiviral dimer 3'-azido-3'-deoxythymidine-P-2',3'-dideoxyinosine and the monomers zidovudine and didanosine by rat, monkey, and human hepatocytes
2 Elucidation of urinary metabolites of fluoxymesterone by liquid chromatography-tandem mass spectrometry and gas chromatography-mass spectrometry
3 Metabolism of nicotinamide, adenine and inosine in developing microspore-derived canola (Brassica napus) embryos
4 Inosine in Biology and Disease
5 Utilization of naproxen by Amycolatopsis sp. Poz 14 and detection of the enzymes involved in the degradation metabolic pathway
6 Adenosine Metabolism: Emerging Concepts for Cancer Therapy Cancer Cell. 2019 Dec 9;36(6):582-596. doi: 10.1016/j.ccell.2019.10.007.
7 Purine signaling pathway dysfunction in autism spectrum disorders: Evidence from multiple omics data. Front Mol Neurosci. 2023 Feb 3;16:1089871. doi: 10.3389/fnmol.2023.1089871.

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