Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005041)
Formula
SVG example
4'-hydroxylation
Reactant Flurbiprofen sodium Product 4'-Hydroxyflurbiprofen
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2C9 (CYP2C9) DME Info
Metabolic Type Oxidation - 4'-hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005044 Flurbiprofen sodium Flurbiprofen glucuronide Conjugation - Glucuronidation Flurbiprofen sodium [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011802 R-flurbiprofen 4'-hydroxyflurbiprofen Unclear - Unclear R-flurbiprofen [2]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005042 4'-Hydroxyflurbiprofen 3',4'-dihydroxyflurbiprofen Unclear Flurbiprofen sodium [3]
References
1 DrugBank(Pharmacology-Metabolism):Flurbiprofen
2 Stereoselective disposition of flurbiprofen in normal volunteers
3 Disposition of flurbiprofen in man: influence of stereochemistry and age

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