Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005114)
Formula
SVG example
6-ketoreduction
Reactant Hydrocodone bitartrate Product 6-alpha-hydrocodol
Reactant Info Product Info
Metabolic Type Reduction - 6-ketoreduction
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005109 Hydrocodone bitartrate Hydromorphone Oxidation - O-demethylation Hydrocodone bitartrate [1]
MR005123 Hydrocodone bitartrate Norhydrocodone Oxidation - N-demethylation Hydrocodone bitartrate [1]
MR005115 Hydrocodone bitartrate 6-beta-hydrocodol Reduction - 6-ketoreduction Hydrocodone bitartrate [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005118 6-alpha-hydrocodol 6-alpha-hydromorphol Oxidation - O-demethylation Hydrocodone bitartrate [2]
References
1 CYP2D6 and CYP3A4 involvement in the primary oxidative metabolism of hydrocodone by human liver microsomes. Br J Clin Pharmacol. 2004 Mar;57(3):287-97.
2 DrugBank(Pharmacology-Metabolism):Hydrocodone bitartrate

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