Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005389)
Formula
	Reactant	Abrocitinib M4 metabolite	Product	Abrocitinib M8 metabolite
	Reactant	Reactant Info	Product	Product Info

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR005388	PF-04965842	Abrocitinib M4 metabolite	Oxidation - Oxidationn	PF-04965842	[1]

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR005391	Abrocitinib M4 metabolite	2XOH	Unclear	PF-04965842	[2]

Other MR(s) Related to The Product of This MR

Other MR(s) That Produce The Product of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR005396	Abrocitinib M1 metabolite	Abrocitinib M8 metabolite	Unclear	PF-04965842	[2]

Other MR(s) That Metabolize The Produtc of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR005390	Abrocitinib M8 metabolite	Abrocitinib M6 metabolite	Unclear	PF-04965842	[2]

References
1	Validation of enantioseparation and quantitation of an active metabolite of abrocitinib in human plasma
2	The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Abrocitinib, a Selective Janus Kinase Inhibitor, in Humans

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