Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005391)
Formula Reactant Abrocitinib M4 metabolite Product 2XOH
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005388 PF-04965842 Abrocitinib M4 metabolite Oxidation - Oxidationn PF-04965842 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005389 Abrocitinib M4 metabolite Abrocitinib M8 metabolite Unclear PF-04965842 [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005392 2XOH 3XOH Unclear PF-04965842 [2]
References
1 Validation of enantioseparation and quantitation of an active metabolite of abrocitinib in human plasma
2 The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Abrocitinib, a Selective Janus Kinase Inhibitor, in Humans

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