Details of the Metabolic Reaction (MR)
| General Information of This Metabolic Reaction (MR) (ID: MR005619) | ||||||
|---|---|---|---|---|---|---|
| Formula | Reactant | Selumetinib M12 (Primary amide, N-demethylated selumetinib metabolite) | Product | Selumetinib M13 (Primary amide, N-demethylated, mono-oxidized selumetinib metabolite) | ||
| Reactant Info | Product Info | |||||
| Metabolic Type | Oxidation - Oxidationn | |||||
| Other MR(s) Related to The Reactant of This MR | |||||||||||||||||||||||||||||||||||
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| Other MR(s) That Produce The Reactant of This MR | |||||||||||||||||||||||||||||||||||
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| Other MR(s) That Metabolize The Reactant of This MR | |||||||||||||||||||||||||||||||||||
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| References | ||||||
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| 1 | Metabolism, Excretion, and Pharmacokinetics of Selumetinib, an MEK1/2 inhibitor, in Healthy Adult Male Subjects | |||||
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