Details of the Metabolic Reaction (MR)
General Information of This Metabolic Reaction (MR) (ID: MR005623) | ||||||
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Formula | Reactant | Selumetinib M8 (N-desmethyl selumetinib) | Product | Selumetinib M11 (N-demethylated carboxylic acid selumetinib metabolite) | ||
Reactant Info | Product Info | |||||
Metabolic Type | Oxidation - Oxidationn | |||||
Other MR(s) Related to The Reactant of This MR | |||||||||||||||||||||||||||||||||||||||||
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Other MR(s) That Produce The Reactant of This MR | |||||||||||||||||||||||||||||||||||||||||
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Other MR(s) That Metabolize The Reactant of This MR | |||||||||||||||||||||||||||||||||||||||||
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References | ||||||
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1 | Metabolism, Excretion, and Pharmacokinetics of Selumetinib, an MEK1/2 inhibitor, in Healthy Adult Male Subjects |
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