Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006778)
Formula Reactant 4-Hydroxy tolbutamide Product 4-Carboxytolbutamide
Reactant Info Product Info
Metabolic Enzyme Alcohol dehydrogenase (ADH) DME Info
Aldehyde dehydrogenase (ALDH) DME Info
Aldehyde oxidase (AOX1) DME Info
Xanthine dehydrogenase/oxidase (XDH) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006775 Tolbutamide 4-Hydroxy tolbutamide Oxidation - Hydrolyzationn Tolbutamide [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006776 4-Hydroxy tolbutamide 1-butyl-3-(p-formylphenyl)sulphonylurea Unclear Tolbutamide [2]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
2 A new aspect of tolbutamide metabolism in the rabbit: the role of 1-butyl-3-(p-formylphenyl)sulphonylurea

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.