Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008150)
Formula Reactant Hydroxyvitamin K1 Product Phylloquinone carboxylic acid metabolite
Reactant Info Product Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008149 Phytonadione Hydroxyvitamin K1 Oxidation - Hydroxylation Phytonadione [1], [2], [3], [4], [5]
References
1 Metabolism of vitamin K1 (phylloquinone) in man
2 Vitamin K nutrition, metabolism, and requirements: current concepts and future research
3 Dietary reference values for vitamin K
4 Preparative isolation and characterization of the urinary aglycones of vitamin K1 (phylloquinone in man
5 Cytochrome P450-dependent catabolism of vitamin K: -hydroxylation catalyzed by human CYP4F2 and CYP4F11

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