Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008681)
Formula
CYP2B6 ...
SVG example
Deethylation
Reactant Arteether Product Dihydroqinghaosu (DQHS)
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2B6 (CYP2B6) DME Info
Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Metabolic Type Oxidation - Deethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008688 Arteether 14-Hydroxyarteether Oxidation - Hydroxylation Arteether [1]
MR008687 Arteether 2alpha-Hydroxyarteether Oxidation - Hydroxylation Arteether [1]
MR008684 Arteether 3alpha-Hydroxydeoxyarteether Unclear - Unclear Arteether [1]
MR008686 Arteether 9alpha-Hydroxyarteether Oxidation - Hydroxylation Arteether [1]
MR008685 Arteether 9beta-Hydroxyarteether Oxidation - Hydroxylation Arteether [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008682 Dihydroqinghaosu (DQHS) Deoxydihydro-artemisinin Unclear - Unclear Arteether [1]
References
1 Synthesis, characterization, and antimalarial activity of the glucuronides of the hydroxylated metabolites of arteether

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