Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008684)
Formula
SVG example
Unclear
Reactant Arteether Product 3alpha-Hydroxydeoxyarteether
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008688 Arteether 14-Hydroxyarteether Oxidation - Hydroxylation Arteether [1]
MR008687 Arteether 2alpha-Hydroxyarteether Oxidation - Hydroxylation Arteether [1]
MR008686 Arteether 9alpha-Hydroxyarteether Oxidation - Hydroxylation Arteether [1]
MR008685 Arteether 9beta-Hydroxyarteether Oxidation - Hydroxylation Arteether [1]
MR008681 Arteether Dihydroqinghaosu (DQHS) Oxidation - Deethylation Arteether [2], [1]
References
1 Synthesis, characterization, and antimalarial activity of the glucuronides of the hydroxylated metabolites of arteether
2 Metabolism of beta-arteether to dihydroqinghaosu by human liver microsomes and recombinant cytochrome P450

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