Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008687)
Formula
SVG example
Hydroxylation
Reactant Arteether Product 2alpha-Hydroxyarteether
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008688 Arteether 14-Hydroxyarteether Oxidation - Hydroxylation Arteether [1]
MR008684 Arteether 3alpha-Hydroxydeoxyarteether Unclear - Unclear Arteether [1]
MR008686 Arteether 9alpha-Hydroxyarteether Oxidation - Hydroxylation Arteether [1]
MR008685 Arteether 9beta-Hydroxyarteether Oxidation - Hydroxylation Arteether [1]
MR008681 Arteether Dihydroqinghaosu (DQHS) Oxidation - Deethylation Arteether [2], [1]
References
1 Synthesis, characterization, and antimalarial activity of the glucuronides of the hydroxylated metabolites of arteether
2 Metabolism of beta-arteether to dihydroqinghaosu by human liver microsomes and recombinant cytochrome P450

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