Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR009261)
Formula	Unclear
	Reactant	Neupro		Product	Neupro Metabolite M4
	Reactant	Reactant Info		Product	Product Info
Metabolic Type	Unclear - Unclear

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR009255	Neupro	N-despropyl-rotigotine	Unclear - Unclear	Neupro	[1], [2]
MR009258	Neupro	N-desthienylethyl-rotigotine	Unclear - Unclear	Neupro	[1]
MR009262	Neupro	Neupro Metabolite M5	Unclear - Unclear	Neupro	[1], [3]

References
1	Absorption, disposition, metabolic fate, and elimination of the dopamine agonist rotigotine in man: administration by intravenous infusion or transdermal delivery
2	No influence of the CYP2C19-selective inhibitor omeprazole on the pharmacokinetics of the dopamine receptor agonist rotigotine
3	Identification of the human SULT enzymes involved in the metabolism of rotigotine. J Clin Pharmacol. 2016 Jun;56(6):754-60.

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