Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009262)
Formula
SULT1A1 ...
SVG example
Unclear
Reactant Neupro Product Neupro Metabolite M5
Reactant Info Product Info
Metabolic Enzyme Sulfotransferase 1A1 (SULT1A1) DME Info
Sulfotransferase 1A2 (SULT1A2) DME Info
Sulfotransferase 1A3 (SULT1A3) DME Info
Sulfotransferase 1B1 (SULT1B1) DME Info
Sulfotransferase 1C4 (SULT1C4) DME Info
Sulfotransferase 1E1 (SULT1E1) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009255 Neupro N-despropyl-rotigotine Unclear - Unclear Neupro [1], [2]
MR009258 Neupro N-desthienylethyl-rotigotine Unclear - Unclear Neupro [1]
MR009261 Neupro Neupro Metabolite M4 Unclear - Unclear Neupro [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010612 N-0923 N-0923 Metabolite M10 Unclear - Unclear N-0923 [3]
References
1 Absorption, disposition, metabolic fate, and elimination of the dopamine agonist rotigotine in man: administration by intravenous infusion or transdermal delivery
2 No influence of the CYP2C19-selective inhibitor omeprazole on the pharmacokinetics of the dopamine receptor agonist rotigotine
3 Determination of the dopamine D2 agonist N-0923 and its major metabolites in perfused rat livers by HPLC-UV-atmospheric pressure ionization mass spectrometry

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