Details of the Metabolic Reaction (MR)
| General Information of This Metabolic Reaction (MR) (ID: MR009841) | ||||||
|---|---|---|---|---|---|---|
| Formula | Reactant | Alpelisib | Product | Alpelisib Metabolite M12 | ||
| Reactant Info | Product Info | |||||
| Metabolic Enzyme | UDP-glucuronosyltransferase 1A9 (UGT1A9) | DME Info | ||||
| Metabolic Type | Conjugation - N-Glucuronidation | |||||
| Other MR(s) Related to The Reactant of This MR | |||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Other MR(s) That Metabolize The Reactant of This MR | |||||||||||||||||||||||||||||||||||||||||||||||||||||
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| References | ||||||
|---|---|---|---|---|---|---|
| 1 | Absorption, distribution, metabolism, and excretion of [(14)C]BYL719 (alpelisib) in healthy male volunteers. Cancer Chemother Pharmacol. 2015 Oct;76(4):751-60. | |||||
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