Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009945)
Formula
SVG example
Unclear
Reactant Aldophosphamide Product Carboxyphosphamide
Reactant Info Product Info
Metabolic Enzyme Aldehyde dehydrogenase (ALDH) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009943 4-Hydroxycyclophosphamide Aldophosphamide Unclear - Unclear Cyclophosphamide [1]
MR012898 4-Hydroxycyclophosphamide Aldophosphamide Unclear Cyclobenzaprine [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009946 Aldophosphamide Acrolein Unclear - Unclear Cyclophosphamide [1]
MR012901 Aldophosphamide Acrolein Unclear Cyclobenzaprine [2]
MR012905 Aldophosphamide Alcophosphamide Unclear Cyclobenzaprine [3]
MR009944 Aldophosphamide Phosphamide mustard Unclear - Unclear Cyclophosphamide [1]
MR012899 Aldophosphamide Phosphoramide Mustard Unclear Cyclobenzaprine [4]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012904 Carboxyphosphamide Nornitrogen mustard Unclear Cyclobenzaprine [3]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
2 The KEGG resource for deciphering the genome
3 U. S. FDA Label -Cyclobenzaprine
4 DrugBank(Pharmacology-Metabolism):Cyclobenzaprine

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