Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012905)
Formula
ADH1A ...
SVG example
Reactant Aldophosphamide Product Alcophosphamide
Reactant Info Product Info
Metabolic Enzyme Alcohol dehydrogenase class-I alpha (ADH1A) DME Info
Aldo-keto reductase 1A1 (AKR1A1) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009943 4-Hydroxycyclophosphamide Aldophosphamide Unclear - Unclear Cyclophosphamide [1]
MR012898 4-Hydroxycyclophosphamide Aldophosphamide Unclear Cyclobenzaprine [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009946 Aldophosphamide Acrolein Unclear - Unclear Cyclophosphamide [1]
MR012901 Aldophosphamide Acrolein Unclear Cyclobenzaprine [2]
MR009945 Aldophosphamide Carboxyphosphamide Unclear - Unclear Cyclophosphamide [1]
MR012903 Aldophosphamide Carboxyphosphamide Unclear Cyclobenzaprine [3]
MR009944 Aldophosphamide Phosphamide mustard Unclear - Unclear Cyclophosphamide [1]
MR012899 Aldophosphamide Phosphoramide Mustard Unclear Cyclobenzaprine [4]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
2 The KEGG resource for deciphering the genome
3 U. S. FDA Label -Cyclobenzaprine
4 DrugBank(Pharmacology-Metabolism):Cyclobenzaprine

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