Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011217)
Formula
SVG example
Ketone reduction
Reactant Norhydrocodone Product Norhydrocodol
Reactant Info Product Info
Metabolic Type Reduction - Ketone reduction
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011205 Hydrocodone Norhydrocodone Oxidation - N-demethylation Hydrocodone [1]
MR005123 Hydrocodone bitartrate Norhydrocodone Oxidation - N-demethylation Hydrocodone bitartrate [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011206 Norhydrocodone Hydrocodone M272 Multi-steps Reaction - N-demethylation; O-demethylation Hydrocodone [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011214 Hydrocodol Norhydrocodol Oxidation - N-demethylation Hydrocodone [1]
References
1 Update on hydrocodone metabolites in rats and dogs aided with a semi-automatic software for metabolite identification Mass-MetaSite
2 CYP2D6 and CYP3A4 involvement in the primary oxidative metabolism of hydrocodone by human liver microsomes. Br J Clin Pharmacol. 2004 Mar;57(3):287-97.

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