Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012303)
Formula Reactant LIK-066 Product LIK-066 M22
Reactant Info Product Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012308 LIK-066 LIK-066 M12,15 Multi-steps Reaction - Oxidation; Dioxine oxidation ring opening LIK-066 [1]
MR012306 LIK-066 LIK-066 M13,14 Oxidation - Oxidation LIK-066 [1]
MR012315 LIK-066 LIK-066 M17,27 Multi-steps Reaction - Oxidation; direct glucuronidation LIK-066 [1]
MR012311 LIK-066 LIK-066 M20,M21 Multi-steps Reaction - Oxidation; Dioxine oxidation ring opening LIK-066 [1]
MR012314 LIK-066 LIK-066 M28 Multi-steps Reaction - Oxidation; Desaturation LIK-066 [1]
MR012313 LIK-066 LIK-066 M7 Multi-steps Reaction - O-dealkylation; Dioxine oxidation ring opening; glucurondation LIK-066 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012304 LIK-066 M22 LIK-066 M10,18,41 Conjugation - Glucuronidation LIK-066 [1]
References
1 Pharmacokinetics, metabolism, and excretion of licogliflozin, a dual inhibitor of SGLT1/2, in rats, dogs, and humans

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