Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012872)
Formula
SVG example
Reactant Ethylmorphine Product Norethylmorphine
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012878 Ethylmorphine Ethylmorphine-6-glucuronide Unclear Ethylmorphine [1]
MR012868 Ethylmorphine Morphine Oxidation - N-dealkylation Ethylmorphine [2], [3], [4], [5]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012877 Norethylmorphine Norethylmorphine-6-glucuronide Unclear Ethylmorphine [1]
MR012873 Norethylmorphine Normorphine Unclear Ethylmorphine [1]
MR012876 Norethylmorphine Normorphine-3-glucuronide Conjugation - Glucuronidation Ethylmorphine [2]
References
1 Biotransformation and pharmacokinetics of ethylmorphine after a single oral dose. Br J Clin Pharmacol. 1995 Jun;39(6):611-20.
2 Ethylmorphine metabolism in isolated rat hepatocytes
3 Urinary excretion of codeine, ethylmorphine, and their metabolites: relation to the CYP2D6 activity
4 Pharmacogenomics knowledge for personalized medicine Clin Pharmacol Ther. 2012 Oct;92(4):414-7. doi: 10.1038/clpt.2012.96.
5 Metabolism and pharmacokinetics of morphine in neonates: A review

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