Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012953)
Formula
SVG example
Reactant ICYS Product Ibrutinib-S-glucuronide
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 1A1 (UGT1A1) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012948 ICGS ICYS Unclear Ibrutinib [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012952 ICYS Ibrutinib sulphenic acid Unclear Ibrutinib [1]
MR012951 ICYS Ibrutinib-mercapturic acid Unclear Ibrutinib [1]
MR012949 ICYS Ibrutinib-SH Unclear Ibrutinib [1]
References
1 Extrahepatic metabolism of ibrutinib

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