Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013704)
Formula
SULT1A2 ...
SVG example
Sulfation
Reactant Opicapone Product BIA 9-1103
Reactant Info Product Info
Metabolic Enzyme Sulfotransferase 1A2 (SULT1A2) DME Info
Sulfotransferase 1A3 (SULT1A3) DME Info
Sulfotransferase 2A1 (SULT2A1) DME Info
Sulfotransferase 1E1 (SULT1E1) DME Info
Sulfotransferase 1B1 (SULT1B1) DME Info
Metabolic Type Conjugation - Sulfation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013696 Opicapone BIA 9-1079 Reduction - Reduction Opicapone [1]
MR013706 Opicapone BIA 9-1100 Oxidation - Methylation Opicapone [1]
MR013707 Opicapone BIA 9-1101 Multi-steps Reaction - Methylation; reduction Opicapone [1]
MR013705 Opicapone BIA 9-1104 Oxidation - Methylation Opicapone [1]
MR013702 Opicapone BIA 9-1106 Conjugation - Glucuronidation Opicapone [1]
References
1 Pharmacokinetics, pharmacodynamics and tolerability of opicapone, a novel catechol-O-methyltransferase inhibitor, in healthy subjects: prediction of slow enzyme-inhibitor complex dissociation of a short-living and very long-acting inhibitor

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