Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR013706)
Formula	Methylation
	Reactant	Opicapone		Product	BIA 9-1100
	Reactant	Reactant Info		Product	Product Info
Metabolic Type	Oxidation - Methylation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR013696	Opicapone	BIA 9-1079	Reduction - Reduction	Opicapone	[1]
MR013707	Opicapone	BIA 9-1101	Multi-steps Reaction - Methylation; reduction	Opicapone	[1]
MR013704	Opicapone	BIA 9-1103	Conjugation - Sulfation	Opicapone	[1]
MR013705	Opicapone	BIA 9-1104	Oxidation - Methylation	Opicapone	[1]
MR013702	Opicapone	BIA 9-1106	Conjugation - Glucuronidation	Opicapone	[1]

References
1	Pharmacokinetics, pharmacodynamics and tolerability of opicapone, a novel catechol-O-methyltransferase inhibitor, in healthy subjects: prediction of slow enzyme-inhibitor complex dissociation of a short-living and very long-acting inhibitor

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