Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO02336)
Xenobiotics Name
Aurein-1.2
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Azoreductase (azoR) DME Info Escherichia coli [1]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [1]
Beta-lactamase (blaB) DME Info Escherichia coli [1]
Chloramphenicolase (chlR) DME Info Escherichia coli [1]
Glycoside hydrolase (cscA) DME Info Escherichia coli [1]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [1]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [1]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [1]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [1]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [1]
Glutamate racemase (MurI) DME Info Escherichia coli [1]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [1]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [1]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [1]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [3]
Tyramine oxidase (tynA) DME Info Escherichia coli [1]
Beta-glucuronidase (uidA) DME Info Escherichia coli [1]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Azoreductase (azoR) DME Info MIC = 8 microM [1]
L,D-carboxypeptidase A (ldcA) DME Info MIC = 8 microM [1]
Beta-lactamase (blaB) DME Info MIC = 8 microM [1]
Chloramphenicolase (chlR) DME Info MIC = 8 microM [1]
Glycoside hydrolase (cscA) DME Info MIC = 8 microM [1]
NADPH-dependent curcumin reductase (curA) DME Info MIC = 8 microM [1]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 8 microM [1]
Glutamate decarboxylase (gadB) DME Info MIC = 8 microM [1]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 8 microM [1]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 8 microM [1]
Glutamate racemase (MurI) DME Info MIC = 8 microM [1]
N-ethylmaleimide reductase (nemA) DME Info MIC = 8 microM [1]
NADPH-dependent oxidoreductase (nfrA) DME Info MIC = 8 microM [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 8 microM [1]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 8 microM [1]
NADH dehydrogenase (nuoE) DME Info MIC = 8 microM [3]
Tyramine oxidase (tynA) DME Info MIC = 8 microM [1]
Beta-glucuronidase (uidA) DME Info MIC = 8 microM [1]
References
1 Correlation of three-dimensional structures with the antibacterial activity of a group of peptides designed based on a nontoxic bacterial membrane anchor. J Biol Chem. 2005 Feb 18;280(7):5803-11.
2 Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance. Peptides. 2004 Jun;25(6):1035-54.
3 The antibiotic and anticancer active aurein peptides from the Australian Bell Frogs Litoria aurea and Litoria raniformis the solution structure of aurein 1.2. Eur J Biochem. 2000 Sep;267(17):5330-41.

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