Detail Information of Xenobiotics
| General Information of Xenobiotics (ID: XEO02930) | ||||||
|---|---|---|---|---|---|---|
| Xenobiotics Name |
Indolicidin derivative CP10A
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| Xenobiotics Type |
Amino Acid(s), Peptide(s) or Protein(s)
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| Classification |
Peptide
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| DME(s) Modulated by This Xenobiotics | ||||||
| DME(s) Inhibited by This Xenobiotics | ||||||
| Azoreductase (azoR) | DME Info | Enterococcus faecalis | [1] | |||
| Azoreductase (azoR) | DME Info | Streptococcus pyogenes | [1] | |||
| Unclear metabolic mechanism (DME-unclear) | DME Info | Enterococcus faecalis | [1] | |||
| Glutamate decarboxylase (gadB) | DME Info | Listeria monocytogenes | [1] | |||
| NADPH-dependent oxidoreductase (nfrA) | DME Info | Staphylococcus aureus | [1] | |||
| Tyrosine decarboxylase (tdc) | DME Info | Enterococcus faecalis | [1] | |||
| VanA ligase (vanA) | DME Info | Enterococcus faecalis | [1] | |||
| VanB ligase (vanB) | DME Info | Enterococcus faecalis | [1] | |||
| Xenobiotics-DME Activity Data | ||||||
| Xenobiotics-DME Activity Data | Azoreductase (azoR) | DME Info | MIC = 8 ug/ml | [1] | ||
| Azoreductase (azoR) | DME Info | MIC = 1 ug/ml | [1] | |||
| Unclear metabolic mechanism (DME-unclear) | DME Info | MIC = 8 ug/ml | [1] | |||
| Glutamate decarboxylase (gadB) | DME Info | MIC = 1 ug/ml | [1] | |||
| NADPH-dependent oxidoreductase (nfrA) | DME Info | MIC = 4 ug/ml | [1] | |||
| Tyrosine decarboxylase (tdc) | DME Info | MIC = 8 ug/ml | [1] | |||
| VanA ligase (vanA) | DME Info | MIC = 8 ug/ml | [1] | |||
| VanB ligase (vanB) | DME Info | MIC = 8 ug/ml | [1] | |||
| References | ||||||
| 1 | Structure and mechanism of action of an indolicidin peptide derivative with improved activity against gram-positive bacteria. J Biol Chem. 2001 Jun 29;276(26):24015-22. | |||||
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