Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO03644)
Xenobiotics Name
Indole
Xenobiotics Type
Health or Environmental Toxicant(s)
Classification
Acute Toxic Substance
Structure
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3D MOL 2D MOL
PubChem CID
798
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Ampc beta-lactamase (ampC) DME Info Burkholderia cenocepacia [1]
Azoreductase (azoR) DME Info Escherichia coli [2]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [2]
Beta-lactamase (blaB) DME Info Escherichia coli [2]
Chloramphenicolase (chlR) DME Info Escherichia coli [2]
Glycoside hydrolase (cscA) DME Info Escherichia coli [2]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [2]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [2]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [2]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [2]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [3]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [2]
Glutamate racemase (MurI) DME Info Escherichia coli [2]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [3]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [2]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [2]
Beta-lactamase (blaB) DME Info Burkholderia cenocepacia [1]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [3]
Tyramine oxidase (tynA) DME Info Escherichia coli [2]
Beta-glucuronidase (uidA) DME Info Escherichia coli [2]
References
1 Use of quorum sensing inhibitors to interfere with biofilm formation and development in Burkholderia multivorans and Burkholderia cenocepacia. Res Microbiol. 2009 Mar;160(2):144-51.
2 Indole signalling and (micro)algal auxins decrease the virulence of Vibrio campbellii, a major pathogen of aquatic organisms. Environ Microbiol. 2017 May;19(5):1987-2004.
3 Indole derivatives inhibited the formation of bacterial biofilm and modulated Ca2+ efflux in diatom. Mar Pollut Bull. 2014 Nov 15;88(1-2):62-9.

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