Details of Microbiome-DME Interaction (MICBIO)

General Information of Drug-Metabolizing Enzyme (DME ID: DME0020)
DME Name	Cytochrome P450 2B6 (CYP2B6), Homo sapiens	DME Info
UniProt ID	CP2B6_HUMAN
EC Number	EC: 1.14.14.1 (Click to Show/Hide the Complete EC Tree) Oxidoreductase Oxygen paired donor oxidoreductase Flavin/flavoprotein donor oxidoreductase EC: 1.14.14.1
Lineage	Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage) Kingdom: Metazoa Phylum: Chordata Class: Mammalia Order: Primates Family: Hominidae Genus: Homo Species: Homo sapiens
Interactome

Interactions between Microbiome and DME (MICBIO)
Bacteria: Actinobacteria
Bifidobacterium adolescentis (actinobacteria)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bifidobacterium adolescentis co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bifidobacterium adolescentis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Bifidobacterium breve (actinobacteria)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bifidobacterium breve co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bifidobacterium breve co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Bifidobacterium longum (actinobacteria)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bifidobacterium longum co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bifidobacterium longum co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Bifidobacterium ruminatum (actinobacteria)		Click to Show/Hide the Full List of Drugs: 3 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bifidobacterium ruminatum co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Bupropion		Click to Show/Hide the Detail
Drug ID	DR0247 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bifidobacterium ruminatum co-metabolize the drug Bupropion, which can collectively affect efficacy, safety or bioavailability of this drug.		[4], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bifidobacterium ruminatum co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Collinsella intestinalis (actinobacteria)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Collinsella intestinalis co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Eggerthella lenta (actinobacteria)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Eggerthella lenta co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Mycobacterium tuberculosis (actinobacteria)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Dextromethorphan hydrobromide		Click to Show/Hide the Detail
Drug ID	DR0476 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Mycobacterium tuberculosis co-metabolize the drug Dextromethorphan hydrobromide, which can collectively affect efficacy, safety or bioavailability of this drug.		[5], [6]
Nocardia farcinica (actinobacteria)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Rifampicin		Click to Show/Hide the Detail
Drug ID	DR1420 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Nocardia farcinica co-metabolize the drug Rifampicin, which can collectively affect efficacy, safety or bioavailability of this drug.		[7], [8]
Streptomyces avermitilis (actinobacteria)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
Diclofenac sodium		Click to Show/Hide the Detail
Drug ID	DR0488 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Streptomyces avermitilis co-metabolize the drug Diclofenac sodium, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [10], [11]
Testosterone cypionate		Click to Show/Hide the Detail
Drug ID	DR1564 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Streptomyces avermitilis co-metabolize the drug Testosterone cypionate, which can collectively affect efficacy, safety or bioavailability of this drug.		[12], [13], [10]
Bacteria: Bacteroidetes
Alistipes indistinctus (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 4 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Alistipes indistinctus co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Cyclophosphamide		Click to Show/Hide the Detail
Drug ID	DR0391 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Alistipes indistinctus co-metabolize the drug Cyclophosphamide, which can collectively affect efficacy, safety or bioavailability of this drug.		[14], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Alistipes indistinctus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Loperamide hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0974 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Alistipes indistinctus co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[15], [2]
Bacteroides cellulosilyticus (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides cellulosilyticus co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Bacteroides coprophilus (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
Clopidogrel bisulfate		Click to Show/Hide the Detail
Drug ID	DR0355 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides coprophilus co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug.		[16], [2]
Loperamide hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0974 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides coprophilus co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[15], [2]
Bacteroides dorei (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 7 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides dorei co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Clopidogrel bisulfate		Click to Show/Hide the Detail
Drug ID	DR0355 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides dorei co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug.		[16], [2]
Diclofenac sodium		Click to Show/Hide the Detail
Drug ID	DR0488 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) metabolizes the drug Diclofenac sodium, and Bacteroides dorei further metabolizes its metabolite (Diclofenac glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug.		[9], [17]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides dorei co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Loperamide hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0974 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides dorei co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[15], [2]
Phenytoin		Click to Show/Hide the Detail
Drug ID	DR1282 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides dorei co-metabolize the drug Phenytoin, which can collectively affect efficacy, safety or bioavailability of this drug.		[18], [2]
Ritonavir		Click to Show/Hide the Detail
Drug ID	DR1430 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides dorei co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug.		[19], [2]
Bacteroides eggerthii (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 5 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides eggerthii co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Clopidogrel bisulfate		Click to Show/Hide the Detail
Drug ID	DR0355 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides eggerthii co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug.		[16], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides eggerthii co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Loperamide hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0974 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides eggerthii co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[15], [2]
Ritonavir		Click to Show/Hide the Detail
Drug ID	DR1430 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides eggerthii co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug.		[19], [2]
Bacteroides finegoldii (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides finegoldii co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Bacteroides fragilis (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 6 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides fragilis co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Clopidogrel bisulfate		Click to Show/Hide the Detail
Drug ID	DR0355 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides fragilis co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug.		[16], [2]
Cyclophosphamide		Click to Show/Hide the Detail
Drug ID	DR0391 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides fragilis co-metabolize the drug Cyclophosphamide, which can collectively affect efficacy, safety or bioavailability of this drug.		[14], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides fragilis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Loperamide hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0974 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides fragilis co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[15], [2]
Ritonavir		Click to Show/Hide the Detail
Drug ID	DR1430 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides fragilis co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug.		[19], [2]
Bacteroides intestinalis (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides intestinalis co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides intestinalis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Bacteroides ovatus (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 3 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides ovatus co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Clopidogrel bisulfate		Click to Show/Hide the Detail
Drug ID	DR0355 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides ovatus co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug.		[16], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides ovatus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Bacteroides sartorii (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 6 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides sartorii co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Clopidogrel bisulfate		Click to Show/Hide the Detail
Drug ID	DR0355 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides sartorii co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug.		[16], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides sartorii co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Loperamide hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0974 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides sartorii co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[15], [2]
Phenytoin		Click to Show/Hide the Detail
Drug ID	DR1282 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides sartorii co-metabolize the drug Phenytoin, which can collectively affect efficacy, safety or bioavailability of this drug.		[18], [2]
Ritonavir		Click to Show/Hide the Detail
Drug ID	DR1430 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides sartorii co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug.		[19], [2]
Bacteroides stercoris (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 4 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides stercoris co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Clopidogrel bisulfate		Click to Show/Hide the Detail
Drug ID	DR0355 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides stercoris co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug.		[16], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides stercoris co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Loperamide hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0974 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides stercoris co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[15], [2]
Bacteroides thetaiotaomicron (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 5 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides thetaiotaomicron co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Clopidogrel bisulfate		Click to Show/Hide the Detail
Drug ID	DR0355 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides thetaiotaomicron co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug.		[16], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides thetaiotaomicron co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Irinotecan hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0881 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) metabolizes the drug Irinotecan hydrochloride, and Bacteroides thetaiotaomicron further metabolizes its metabolite (SN-38G), which can indirectly affect efficacy, safety or bioavailability of this drug.		[20], [21]
Ritonavir		Click to Show/Hide the Detail
Drug ID	DR1430 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides thetaiotaomicron co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug.		[19], [2]
Bacteroides uniformis (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 3 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides uniformis co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides uniformis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Irinotecan hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0881 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) metabolizes the drug Irinotecan hydrochloride, and Bacteroides uniformis further metabolizes its metabolite (SN-38G), which can indirectly affect efficacy, safety or bioavailability of this drug.		[20], [21]
Bacteroides vulgatus (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 7 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides vulgatus co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Clopidogrel bisulfate		Click to Show/Hide the Detail
Drug ID	DR0355 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides vulgatus co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug.		[16], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides vulgatus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Loperamide hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0974 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides vulgatus co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[15], [2]
Phenytoin		Click to Show/Hide the Detail
Drug ID	DR1282 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides vulgatus co-metabolize the drug Phenytoin, which can collectively affect efficacy, safety or bioavailability of this drug.		[18], [2]
Ritonavir		Click to Show/Hide the Detail
Drug ID	DR1430 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides vulgatus co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug.		[19], [2]
Verapamil hydrochloride		Click to Show/Hide the Detail
Drug ID	DR1681 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides vulgatus co-metabolize the drug Verapamil hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[22], [2]
Bacteroides xylanisolvens (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 6 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides xylanisolvens co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Clopidogrel bisulfate		Click to Show/Hide the Detail
Drug ID	DR0355 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides xylanisolvens co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug.		[16], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides xylanisolvens co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Loperamide hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0974 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides xylanisolvens co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[15], [2]
Phenytoin		Click to Show/Hide the Detail
Drug ID	DR1282 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides xylanisolvens co-metabolize the drug Phenytoin, which can collectively affect efficacy, safety or bioavailability of this drug.		[18], [2]
Ritonavir		Click to Show/Hide the Detail
Drug ID	DR1430 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides xylanisolvens co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug.		[19], [2]
Odoribacter splanchnicus (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 5 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Odoribacter splanchnicus co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Clopidogrel bisulfate		Click to Show/Hide the Detail
Drug ID	DR0355 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Odoribacter splanchnicus co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug.		[16], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Odoribacter splanchnicus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Loperamide hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0974 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Odoribacter splanchnicus co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[15], [2]
Ritonavir		Click to Show/Hide the Detail
Drug ID	DR1430 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Odoribacter splanchnicus co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug.		[19], [2]
Parabacteroides distasonis (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 6 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Parabacteroides distasonis co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Clopidogrel bisulfate		Click to Show/Hide the Detail
Drug ID	DR0355 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Parabacteroides distasonis co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug.		[16], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Parabacteroides distasonis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Loperamide hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0974 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Parabacteroides distasonis co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[15], [2]
Phenytoin		Click to Show/Hide the Detail
Drug ID	DR1282 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Parabacteroides distasonis co-metabolize the drug Phenytoin, which can collectively affect efficacy, safety or bioavailability of this drug.		[18], [2]
Ritonavir		Click to Show/Hide the Detail
Drug ID	DR1430 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Parabacteroides distasonis co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug.		[19], [2]
Parabacteroides johnsonii (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 3 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Parabacteroides johnsonii co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Clopidogrel bisulfate		Click to Show/Hide the Detail
Drug ID	DR0355 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Parabacteroides johnsonii co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug.		[16], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Parabacteroides johnsonii co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Parabacteroides merdae (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 3 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Parabacteroides merdae co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Clopidogrel bisulfate		Click to Show/Hide the Detail
Drug ID	DR0355 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Parabacteroides merdae co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug.		[16], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Parabacteroides merdae co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Prevotella copri (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Prevotella copri co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Prevotella copri co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Bacteria: Firmicutes
Anaerobutyricum hallii (firmicutes)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Anaerobutyricum hallii co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Anaerobutyricum hallii co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Anaerococcus hydrogenalis (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Anaerococcus hydrogenalis co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Anaerostipes hadrus (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Anaerostipes hadrus co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Anaerotruncus colihominis (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Anaerotruncus colihominis co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Bacillus megaterium (firmicutes)		Click to Show/Hide the Full List of Drugs: 3 Drugs Metabolized
Dextromethorphan hydrobromide		Click to Show/Hide the Detail
Drug ID	DR0476 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacillus megaterium co-metabolize the drug Dextromethorphan hydrobromide, which can collectively affect efficacy, safety or bioavailability of this drug.		[5], [23]
Diclofenac sodium		Click to Show/Hide the Detail
Drug ID	DR0488 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacillus megaterium co-metabolize the drug Diclofenac sodium, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [24]
Testosterone cypionate		Click to Show/Hide the Detail
Drug ID	DR1564 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacillus megaterium co-metabolize the drug Testosterone cypionate, which can collectively affect efficacy, safety or bioavailability of this drug.		[12], [25], [26]
Bacteroides pectinophilus (firmicutes)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides pectinophilus co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Bacteroides pectinophilus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Blautia hansenii (firmicutes)		Click to Show/Hide the Full List of Drugs: 7 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Blautia hansenii co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Clopidogrel bisulfate		Click to Show/Hide the Detail
Drug ID	DR0355 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Blautia hansenii co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug.		[16], [2]
Cyclophosphamide		Click to Show/Hide the Detail
Drug ID	DR0391 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Blautia hansenii co-metabolize the drug Cyclophosphamide, which can collectively affect efficacy, safety or bioavailability of this drug.		[14], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Blautia hansenii co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Loperamide hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0974 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Blautia hansenii co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[15], [2]
Nevirapine		Click to Show/Hide the Detail
Drug ID	DR1142 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Blautia hansenii co-metabolize the drug Nevirapine, which can collectively affect efficacy, safety or bioavailability of this drug.		[27], [2]
Ritonavir		Click to Show/Hide the Detail
Drug ID	DR1430 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Blautia hansenii co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug.		[19], [2]
Blautia luti (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Blautia luti co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Clostridioides difficile (firmicutes)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Clostridioides difficile co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Clostridioides difficile co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Clostridium botulinum (firmicutes)		Click to Show/Hide the Full List of Drugs: 6 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Clostridium botulinum co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Clopidogrel bisulfate		Click to Show/Hide the Detail
Drug ID	DR0355 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Clostridium botulinum co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug.		[16], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Clostridium botulinum co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Loperamide hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0974 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Clostridium botulinum co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[15], [2]
Nevirapine		Click to Show/Hide the Detail
Drug ID	DR1142 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Clostridium botulinum co-metabolize the drug Nevirapine, which can collectively affect efficacy, safety or bioavailability of this drug.		[27], [2]
Ritonavir		Click to Show/Hide the Detail
Drug ID	DR1430 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Clostridium botulinum co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug.		[19], [2]
Clostridium perfringens (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Irinotecan hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0881 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) metabolizes the drug Irinotecan hydrochloride, and Clostridium perfringens further metabolizes its metabolite (SN-38G), which can indirectly affect efficacy, safety or bioavailability of this drug.		[20], [28]
Clostridium scindens (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Clostridium scindens co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Clostridium spiroforme (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Clostridium spiroforme co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Clostridium sporogenes (firmicutes)		Click to Show/Hide the Full List of Drugs: 4 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Clostridium sporogenes co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Clopidogrel bisulfate		Click to Show/Hide the Detail
Drug ID	DR0355 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Clostridium sporogenes co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug.		[16], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Clostridium sporogenes co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Loperamide hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0974 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Clostridium sporogenes co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[15], [2]
Clostridium symbiosum (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Clostridium symbiosum co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Coprococcus comes (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Coprococcus comes co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Dorea formicigenerans (firmicutes)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Dorea formicigenerans co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Dorea formicigenerans co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Enterocloster asparagiformis (firmicutes)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Enterocloster asparagiformis co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Enterocloster asparagiformis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Enterocloster bolteae (firmicutes)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Enterocloster bolteae co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Enterocloster bolteae co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Enterococcus faecalis (firmicutes)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Enterococcus faecalis co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Enterococcus faecalis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Erysipelatoclostridium ramosum (firmicutes)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Erysipelatoclostridium ramosum co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Erysipelatoclostridium ramosum co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Eubacterium rectale (firmicutes)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Eubacterium rectale co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Eubacterium rectale co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Eubacterium ventriosum (firmicutes)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Eubacterium ventriosum co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Eubacterium ventriosum co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Faecalibacterium prausnitzii (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Diclofenac sodium		Click to Show/Hide the Detail
Drug ID	DR0488 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) metabolizes the drug Diclofenac sodium, and Faecalibacterium prausnitzii further metabolizes its metabolite (Diclofenac glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug.		[9], [17]
Holdemanella biformis (firmicutes)		Click to Show/Hide the Full List of Drugs: 4 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Holdemanella biformis co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Cyclophosphamide		Click to Show/Hide the Detail
Drug ID	DR0391 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Holdemanella biformis co-metabolize the drug Cyclophosphamide, which can collectively affect efficacy, safety or bioavailability of this drug.		[14], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Holdemanella biformis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Loperamide hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0974 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Holdemanella biformis co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[15], [2]
Hungatella hathewayi (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Hungatella hathewayi co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Lactobacillus reuteri (firmicutes)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Lactobacillus reuteri co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Lactobacillus reuteri co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Lactobacillus rhamnosus (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Diclofenac sodium		Click to Show/Hide the Detail
Drug ID	DR0488 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) metabolizes the drug Diclofenac sodium, and Lactobacillus rhamnosus further metabolizes its metabolite (Diclofenac glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug.		[9], [17]
Marvinbryantia formatexigens (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Marvinbryantia formatexigens co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Roseburia intestinalis (firmicutes)		Click to Show/Hide the Full List of Drugs: 3 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Roseburia intestinalis co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Roseburia intestinalis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Loperamide hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0974 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Roseburia intestinalis co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[15], [2]
Ruminococcus gnavus (firmicutes)		Click to Show/Hide the Full List of Drugs: 3 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Ruminococcus gnavus co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Diclofenac sodium		Click to Show/Hide the Detail
Drug ID	DR0488 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) metabolizes the drug Diclofenac sodium, and Ruminococcus gnavus further metabolizes its metabolite (Diclofenac glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug.		[9], [17]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Ruminococcus gnavus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Ruminococcus lactaris (firmicutes)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Ruminococcus lactaris co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Ruminococcus lactaris co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Ruminococcus torques (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Ruminococcus torques co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Streptococcus agalactiae (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Irinotecan hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0881 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) metabolizes the drug Irinotecan hydrochloride, and Streptococcus agalactiae further metabolizes its metabolite (SN-38G), which can indirectly affect efficacy, safety or bioavailability of this drug.		[20], [28]
Subdoligranulum variabile (firmicutes)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Subdoligranulum variabile co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Subdoligranulum variabile co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Bacteria: Lentisphaerae
Victivallis vadensis (PVC bacteria)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Victivallis vadensis co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Bacteria: Proteobacteria
Edwardsiella tarda (enterobacteria)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Edwardsiella tarda co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Enterobacter cancerogenus (enterobacteria)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Enterobacter cancerogenus co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Enterobacter cancerogenus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Escherichia coli (enterobacteria)		Click to Show/Hide the Full List of Drugs: 10 Drugs Metabolized
AN-16649		Click to Show/Hide the Detail
Drug ID	DR0173 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Escherichia coli co-metabolize the drug AN-16649, which can collectively affect efficacy, safety or bioavailability of this drug.		[29], [30]
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Escherichia coli co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Bupropion		Click to Show/Hide the Detail
Drug ID	DR0247 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Escherichia coli co-metabolize the drug Bupropion, which can collectively affect efficacy, safety or bioavailability of this drug.		[4], [2]
Flunitrazepam		Click to Show/Hide the Detail
Drug ID	DR0712 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Escherichia coli co-metabolize the drug Flunitrazepam, which can collectively affect efficacy, safety or bioavailability of this drug.		[31], [32]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Escherichia coli co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Irinotecan hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0881 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) metabolizes the drug Irinotecan hydrochloride, and Escherichia coli further metabolizes its metabolite (SN-38G), which can indirectly affect efficacy, safety or bioavailability of this drug.		[20], [33]
Irinotecan hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0881 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Escherichia coli co-metabolize the drug Irinotecan hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[20], [33]
Loperamide hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0974 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Escherichia coli co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[15], [2]
Loperamide hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0974 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Escherichia coli co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[15], [34]
Ritonavir		Click to Show/Hide the Detail
Drug ID	DR1430 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Escherichia coli co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug.		[19], [2]
Proteus penneri (enterobacteria)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Proteus penneri co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Proteus penneri co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Providencia alcalifaciens (enterobacteria)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Providencia alcalifaciens co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Providencia rettgeri (enterobacteria)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Providencia rettgeri co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Loperamide hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0974 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Providencia rettgeri co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[15], [2]
Providencia stuartii (enterobacteria)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Providencia stuartii co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Providencia stuartii co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Pseudomonas putida (gamma-proteobacteria)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Nicotine		Click to Show/Hide the Detail
Drug ID	DR1148 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Pseudomonas putida co-metabolize the drug Nicotine, which can collectively affect efficacy, safety or bioavailability of this drug.		[35], [36]
Salmonella enterica (enterobacteria)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Salmonella enterica co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Fluoxetine hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0720 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Salmonella enterica co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[3], [2]
Bacteria: Verrucomicrobia
Akkermansia muciniphila (verrucomicrobiae)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Artemisinin		Click to Show/Hide the Detail
Drug ID	DR0141 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Akkermansia muciniphila co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug.		[1], [2]
Archaea: Euryarchaeota
Methanobrevibacter oralis (methanobacteria)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Rifampicin		Click to Show/Hide the Detail
Drug ID	DR1420 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Methanobrevibacter oralis co-metabolize the drug Rifampicin, which can collectively affect efficacy, safety or bioavailability of this drug.		[7], [37]
Methanobrevibacter smithii (methanobacteria)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Rifampicin		Click to Show/Hide the Detail
Drug ID	DR1420 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Methanobrevibacter smithii co-metabolize the drug Rifampicin, which can collectively affect efficacy, safety or bioavailability of this drug.		[7], [37]
Methanomassiliicoccus luminyensis (thermoplasmata)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Rifampicin		Click to Show/Hide the Detail
Drug ID	DR1420 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Methanomassiliicoccus luminyensis co-metabolize the drug Rifampicin, which can collectively affect efficacy, safety or bioavailability of this drug.		[7], [37]
Methanosphaera stadtmanae (methanobacteria)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Rifampicin		Click to Show/Hide the Detail
Drug ID	DR1420 Drug Info
Interaction Mechanism	Human Cytochrome P450 2B6 (CYP2B6) and Methanosphaera stadtmanae co-metabolize the drug Rifampicin, which can collectively affect efficacy, safety or bioavailability of this drug.		[7], [37]

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