General Information of Drug Metabolite (DM) (ID: DM001365)
DM Name
Amprenavir metabolite M2
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Cytochrome P450 2C9 (CYP2C9) DME0019 Unclear - Unclear Amprenavir [1]
Cytochrome P450 3A4 (CYP3A4) DME0001 Unclear - Unclear Amprenavir [1]
Cytochrome P450 3A5 (CYP3A5) DME0012 Unclear - Unclear Amprenavir [1]
Full List of Drug(s) That Produce This DM By Metabolism
Amprenavir DR0107 Approved Human immunodeficiency virus infection
References
1 Oxidative metabolism of amprenavir in the human liver. Effect of the CYP3A maturation. Drug Metab Dispos. 2003 Mar;31(3):275-81.

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