Details of the Drug Metabolite (DM)

General Information of Drug Metabolite (DM) (ID: DM001365)
DM Name	Amprenavir metabolite M2

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
Cytochrome P450 2C9 (CYP2C9)	DME0019	Amprenavir	Unclear - Unclear	Amprenavir	[1]
Cytochrome P450 3A4 (CYP3A4)	DME0001	Amprenavir	Unclear - Unclear	Amprenavir	[1]
Cytochrome P450 3A5 (CYP3A5)	DME0012	Amprenavir	Unclear - Unclear	Amprenavir	[1]

Full List of Drug(s) That Produce This DM By Metabolism
Amprenavir		DR0107	Approved		Human immunodeficiency virus infection

References
1	Oxidative metabolism of amprenavir in the human liver. Effect of the CYP3A maturation. Drug Metab Dispos. 2003 Mar;31(3):275-81.

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