| General Information of Drug Metabolite (DM) (ID: DM005759) |
| DM Name |
Oxy-oliceridine
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
|
Cytochrome P450 2C9 (CYP2C9)
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DME0019
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| Oxidation - Oxidationn |
TRV-130
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[1] |
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Cytochrome P450 2D6 (CYP2D6)
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DME0009
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| Oxidation - Oxidationn |
TRV-130
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[1] |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - Oxidationn |
TRV-130
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[1] |
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Mephenytoin 4-hydroxylase (CYP2C19)
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DME0021
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| Oxidation - Oxidationn |
TRV-130
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| TRV-130 |
DR1775
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Phase 1/2 |
Hypothyroidism |
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| References |
| 1 |
The Utilization of Mu-Opioid Receptor Biased Agonists: Oliceridine, an Opioid Analgesic with Reduced Adverse Effects
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