Details of the Drug Metabolite (DM) | INTEDE

General Information of Drug Metabolite (DM) (ID: DM007011)
DM Name	Nomifensine H1

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
Cytochrome P450 1A2 (CYP1A2)	DME0003	Nomifensine	Unclear - Unclear	Nomifensine	[1]
Cytochrome P450 2B6 (CYP2B6)	DME0020	Nomifensine	Unclear - Unclear	Nomifensine	[1]
Cytochrome P450 3A4 (CYP3A4)	DME0001	Nomifensine	Unclear - Unclear	Nomifensine	[1]
Mephenytoin 4-hydroxylase (CYP2C19)	DME0021	Nomifensine	Unclear - Unclear	Nomifensine	[1]

Full List of Drug(s) That Produce This DM By Metabolism
Nomifensine		DR2517	Discontinued		Depression

References
1	In vitro metabolism studies of nomifensine monooxygenation pathways: metabolite identification, reaction phenotyping, and bioactivation mechanism

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