General Information of Drug Metabolite (DM) (ID: DM007011)
DM Name
Nomifensine H1
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Cytochrome P450 1A2 (CYP1A2) DME0003 Unclear - Unclear Nomifensine [1]
Cytochrome P450 2B6 (CYP2B6) DME0020 Unclear - Unclear Nomifensine [1]
Cytochrome P450 3A4 (CYP3A4) DME0001 Unclear - Unclear Nomifensine [1]
Mephenytoin 4-hydroxylase (CYP2C19) DME0021 Unclear - Unclear Nomifensine [1]
Full List of Drug(s) That Produce This DM By Metabolism
Nomifensine DR2517 Discontinued Depression
References
1 In vitro metabolism studies of nomifensine monooxygenation pathways: metabolite identification, reaction phenotyping, and bioactivation mechanism

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