| General Information of Drug Metabolite (DM) (ID: DM017340) |
| DM Name |
4S-Hydroxyevogliptin
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - Hydroxylation |
DA-1229
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[1] |
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Cytochrome P450 3A5 (CYP3A5)
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DME0012
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| Oxidation - Hydroxylation |
DA-1229
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[1] |
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| DME(s) Metabolizing This DM |
| DME Name |
DME ID |
Product |
Reaction |
Related Drug |
REF |
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UDP-glucuronosyltransferase 2B4 (UGT2B4)
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DME0047
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| Conjugation - Glucuronidation |
DA-1229
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[1] |
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UDP-glucuronosyltransferase 2B7 (UGT2B7)
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DME0040
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| Conjugation - Glucuronidation |
DA-1229
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| DA-1229 |
DR3101
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Phase 1 |
Type-2 diabetes |
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| References |
| 1 |
In Vitro Metabolic Pathways of the New Anti-Diabetic Drug Evogliptin in Human Liver Preparations
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