General Information of Drug Metabolite (DM) (ID: DM019524)
DM Name
LN1G
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
UDP-glucuronosyltransferase 1A1 (UGT1A1) DME0004 Unclear - Unclear Losartan [1]
UDP-glucuronosyltransferase 1A3 (UGT1A3) DME0041 Unclear - Unclear Losartan [1]
UDP-glucuronosyltransferase 2B7 (UGT2B7) DME0040 Unclear - Unclear Losartan [1]
Full List of Drug(s) That Produce This DM By Metabolism
Losartan DR3391 Phase 3 Hypertension
References
1 The human UDP-glucuronosyltransferase UGT1A3 is highly selective towards N2 in the tetrazole ring of losartan, candesartan, and zolarsartan. Biochem Pharmacol. 2008 Sep 15;76(6):763-72.

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