General Information of Drug Metabolite (DM) (ID: DM019192)
DM Name
16-OH ganazolone
Structure
3D MOL is unavailable 2D MOL is unavailable
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Cytochrome P450 2B6 (CYP2B6) DME0020 Oxidation - Hydroxylation Ganaxolone [1]
Cytochrome P450 2D6 (CYP2D6) DME0009 Oxidation - Hydroxylation Ganaxolone [1]
Cytochrome P450 3A4 (CYP3A4) DME0001 Oxidation - Hydroxylation Ganaxolone [1]
Cytochrome P450 3A5 (CYP3A5) DME0012 Oxidation - Hydroxylation Ganaxolone [1]
Mephenytoin 4-hydroxylase (CYP2C19) DME0021 Oxidation - Hydroxylation Ganaxolone [1]
Full List of Drug(s) That Produce This DM By Metabolism
Ganaxolone DR3402 Phase 3 Complex partial seizure
References
1 Ganaxolone

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