Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000040)
Formula
SVG example
O-Demethylation
Reactant Acemetacin Product O-demethylatedacemetacin
Reactant Info Product Info
Metabolic Type Oxidation - O-Demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000039 Acemetacin Deacyl indomethacin Other reaction - N-Dehydroxylation; Hydrolysis Acemetacin [1]
MR000042 Acemetacin Indomethacin Hydrolysis - Esterase Hydrolysis Acemetacin [1]
MR000041 Acemetacin O-desmethyl-des-4-chlorobenzoyl Oxidation - Demethylation Acemetacin [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000035 O-demethylatedacemetacin Acemetacin-acyl-beta-D-glucuronide Conjugation - Glucuronidation Acemetacin [1]
MR000036 O-demethylatedacemetacin O-desmethylindometacinsulfate Unclear Acemetacin [2]
References
1 DrugBank(Pharmacology-Metabolism)Acemetacin
2 U. S. FDA Label - Acemetacin

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