Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000158)
Formula
CYP3A4 ...
SVG example
Deamination
Reactant Alogliptin Product Alogliptin M2
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - Deamination
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000157 Alogliptin Alogliptin M1 Oxidation - N-Demethylation Alogliptin [1]
References
1 An update on the clinical pharmacology of the dipeptidyl peptidase 4 inhibitor alogliptin used for the treatment of type 2 diabetes mellitus. Clin Exp Pharmacol Physiol. 2015 Dec;42(12):1225-38.

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