Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000677)
Formula Reactant Cobicistat metabolite M2 Product Cobicistat metabolite M4
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000687 Cobicistat Cobicistat metabolite M2 Unclear Cobicistat [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000676 Cobicistat metabolite M2 Cobicistat metabolite M16 Unclear Cobicistat [1]
References
1 Biotransformation of cobicistat: metabolic pathways and enzymes. Drug Metab Lett. 2016;10(2):111-23.

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