Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000687)
Formula Reactant Cobicistat Product Cobicistat metabolite M2
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000689 Cobicistat Cobicistat metabolite M1 Unclear Cobicistat [1]
MR000688 Cobicistat Cobicistat metabolite M10 Unclear Cobicistat [1]
MR000693 Cobicistat Cobicistat metabolite M11 Unclear Cobicistat [1]
MR000696 Cobicistat Cobicistat metabolite M17 Unclear Cobicistat [1]
MR000694 Cobicistat Cobicistat metabolite M18 Unclear Cobicistat [1]
MR000695 Cobicistat Cobicistat metabolite M19 Unclear Cobicistat [1]
MR000691 Cobicistat Cobicistat metabolite M2-1 Unclear Cobicistat [1]
MR000692 Cobicistat Cobicistat metabolite M2-2 Unclear Cobicistat [1]
MR000685 Cobicistat Cobicistat metabolite M3 Unclear Cobicistat [1]
MR000686 Cobicistat Cobicistat metabolite M9 Unclear Cobicistat [1]
MR000690 Cobicistat Cobicistat metabolite M9-1 Unclear Cobicistat [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000676 Cobicistat metabolite M2 Cobicistat metabolite M16 Unclear Cobicistat [1]
MR000677 Cobicistat metabolite M2 Cobicistat metabolite M4 Unclear Cobicistat [1]
References
1 Biotransformation of cobicistat: metabolic pathways and enzymes. Drug Metab Lett. 2016;10(2):111-23.

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