Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000689)
Formula Reactant Cobicistat Product Cobicistat metabolite M1
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000688 Cobicistat Cobicistat metabolite M10 Unclear Cobicistat [1]
MR000693 Cobicistat Cobicistat metabolite M11 Unclear Cobicistat [1]
MR000696 Cobicistat Cobicistat metabolite M17 Unclear Cobicistat [1]
MR000694 Cobicistat Cobicistat metabolite M18 Unclear Cobicistat [1]
MR000695 Cobicistat Cobicistat metabolite M19 Unclear Cobicistat [1]
MR000687 Cobicistat Cobicistat metabolite M2 Unclear Cobicistat [1]
MR000691 Cobicistat Cobicistat metabolite M2-1 Unclear Cobicistat [1]
MR000692 Cobicistat Cobicistat metabolite M2-2 Unclear Cobicistat [1]
MR000685 Cobicistat Cobicistat metabolite M3 Unclear Cobicistat [1]
MR000686 Cobicistat Cobicistat metabolite M9 Unclear Cobicistat [1]
MR000690 Cobicistat Cobicistat metabolite M9-1 Unclear Cobicistat [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000683 Cobicistat metabolite M1 Cobicistat metabolite 14 Unclear Cobicistat [1]
MR000681 Cobicistat metabolite M1 Cobicistat metabolite M12 Unclear Cobicistat [1]
MR000682 Cobicistat metabolite M1 Cobicistat metabolite M13 Unclear Cobicistat [1]
MR000679 Cobicistat metabolite M1 Cobicistat metabolite M20 Unclear Cobicistat [1]
MR000680 Cobicistat metabolite M1 Cobicistat metabolite M6 Unclear Cobicistat [1]
MR000684 Cobicistat metabolite M1 Cobicistat metabolite M8 Unclear Cobicistat [1]
⏷ Show the Full List of MR
References
1 Biotransformation of cobicistat: metabolic pathways and enzymes. Drug Metab Lett. 2016;10(2):111-23.

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