Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000739)
Formula
SVG example
N-Dealkylation
Reactant Darifenacin hydrobromide Product UK-73,689
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - N-Dealkylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000737 Darifenacin hydrobromide Phenyl hydroxylate Oxidation - Hydroxylation Darifenacin hydrobromide [1]
MR000736 Darifenacin hydrobromide UK-148,993 Oxidation - Hydroxylation Darifenacin hydrobromide [1]
MR000740 Darifenacin hydrobromide UK-222,247 Unclear Darifenacin hydrobromide [1]
MR000738 Darifenacin hydrobromide UK-88,862 Oxidation - N-Dealkylation Darifenacin hydrobromide [1]
References
1 The clinical pharmacokinetics of darifenacin. Clin Pharmacokinet. 2006;45(4):325-50.

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