Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001047)
Formula Reactant Fingolimod hydrochloride Product Non-polar ceramides analogs of fingolimod
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001046 Fingolimod hydrochloride (S)-enantiomer of fingolimod-phosphate Other reaction - Phosphorylation Fingolimod hydrochloride [1], [2]
MR001048 Fingolimod hydrochloride . Unclear Fingolimod hydrochloride [3]
MR001045 Fingolimod hydrochloride Fingolimod carboxylic acid metabolite Oxidation - Hydroxylation Fingolimod hydrochloride [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001042 Fingolimod Non-polar ceramides analogs of fingolimod Unclear Fingolimod [1]
References
1 Clinical pharmacokinetics of fingolimod Clin Pharmacokinet. 2012 Jan 1;51(1):15-28. doi: 10.2165/11596550-000000000-00000.
2 Ketoconazole increases fingolimod blood levels in a drug interaction via CYP4F2 inhibition J Clin Pharmacol. 2009 Feb;49(2):212-8. doi: 10.1177/0091270008329553.
3 LABEL:INGOLIMOD capsule

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