Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001157)
Formula
SVG example
Oxidation
Reactant Hydroquinone Product p-Benzoquinone
Reactant Info Product Info
Metabolic Enzyme Cyclic ADP-ribose hydrolase 1 (CD38) DME Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001158 Hydroquinone 2,3,5-tris(glutathion-S-yl)Hydroquinone Unclear Hydroquinone [1]
MR007415 Hydroquinone Ascorbate Unclear CoQ-10 [2]
MR007416 Hydroquinone Q acid I and Q acid II Unclear CoQ-10 [2]
MR006053 Hydroquinone Quinol glucuronide Conjugation - Conjugation ENT-1814 [3]
MR006052 Hydroquinone Quinol sulfate Conjugation - Conjugation ENT-1814 [3]
MR007414 Hydroquinone Tocopherol Unclear CoQ-10 [2]
MR008147 Hydroquinone Menatetrenone Unclear - Unclear Phytonadione [4]
References
1 Carcinogenicity of a nephrotoxic metabolite of the "nongenotoxic" carcinogen hydroquinone Chem Res Toxicol. 2001 Jan;14(1):25-33. doi: 10.1021/tx000161g.
2 Coenzyme Q10: absorption, tissue uptake, metabolism and pharmacokinetics
3 Cytochrome P450 isozymes involved in the metabolism of phenol, a benzene metabolite. Toxicol Lett. 2001 Dec 15;125(1-3):117-23.
4 Recent trends in the metabolism and cell biology of vitamin K with special reference to vitamin K cycling and MK-4 biosynthesis

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