Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001536)
Formula
SVG example
Reactant Dihydropteroate Product Dihydrofolate
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001538 L-glutamine Dihydropteroate Unclear L-glutamine [1], [2], [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005334 Deoxy-UMP 7,8-dihydrofolate (H2folate) Unclear Deoxy-UMP [4]
MR001083 Folic acid Dihydrofolate Reduction - Reduction Folic acid [5]
References
1 Mutagenesis of folylpolyglutamate synthetase indicates that dihydropteroate and tetrahydrofolate bind to the same site. Biochemistry. 2008 Feb 26;47(8):2388-96.
2 Exploring the contributions of two glutamate decarboxylase isozymes in Lactobacillus brevis to acid resistance and gamma-aminobutyric acid production. Microb Cell Fact. 2018 Nov 19;17(1):180.
3 GABA production and structure of gadB/gadC genes in Lactobacillus and Bifidobacterium strains from human microbiota. Anaerobe. 2016 Dec;42:197-204.
4 Role of the conserved tryptophan 82 of Lactobacillus casei thymidylate synthase. Chem Biol. 1995 Sep;2(9):609-14.
5 DrugBank(Pharmacology-Metabolism)Folic acid

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