Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001636)
Formula
CYP3A4 ...
SVG example
Oxidation
Reactant Megestrol acetate Product Megestrol acetate metabolite M1
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001637 Megestrol acetate Megestrol acetate metabolite M2 Oxidation - Oxidation Megestrol acetate [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001634 Megestrol acetate metabolite M1 Megestrol acetate metabolite MG1 Conjugation - Glucuronidation Megestrol acetate [1]
References
1 Metabolism of megestrol acetate in vitro and the role of oxidative metabolites. Xenobiotica. 2018 Oct;48(10):973-983.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.